Title : Autophagy and Ubiquitin-Mediated Proteolytic Degradation of PML/Rarα Fusion Protein in Matrine-Induced Differentiation Sensitivity Recovery of ATRA-Resistant APL (NB4-LR1) Cells: in Vitro and in Vivo Studies.

Pub. Date : 2018

PMID : 30114705






1 Functional Relationships(s)
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1 RESULTS: MAT improved the sensitivity of NB4-LR1cells to ATRA treatment, which was consistent with the expression of PML-RARalpha fusion protein. Tretinoin PML nuclear body scaffold Homo sapiens