Title : PolyQ Tract Toxicity in SCA1 is Length Dependent in the Absence of CAG Repeat Interruption.

Pub. Date : 2018

PMID : 30108484






5 Functional Relationships(s)
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1 PolyQ Tract Toxicity in SCA1 is Length Dependent in the Absence of CAG Repeat Interruption. polyglutamine ataxin 1 Homo sapiens
2 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by an expansion of a polyglutamine tract within the ATXN1 gene. polyglutamine ataxin 1 Homo sapiens
3 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by an expansion of a polyglutamine tract within the ATXN1 gene. polyglutamine ataxin 1 Homo sapiens
4 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by an expansion of a polyglutamine tract within the ATXN1 gene. polyglutamine ataxin 1 Homo sapiens
5 In addition, the threshold of toxicity shifts to a shorter polyQ length with the increase of the lifespan in SCA1. polyglutamine ataxin 1 Homo sapiens