Title : Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway.

Pub. Date : 2018 Oct

PMID : 30100205






1 Functional Relationships(s)
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1 Here, we demonstrated that TRIM25 interacted with c-Src and underwent tyrosine phosphorylation by c-Src kinase upon viral infection and the phosphorylation is required for the complete activation of RIG-I signaling. Tyrosine C-terminal Src kinase Homo sapiens