Title : Clinical Safety Outcomes in Patients With Nonvalvular Atrial Fibrillation on Rivaroxaban and Diltiazem.

Pub. Date : 2019 Jan

PMID : 30099888






1 Functional Relationships(s)
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1 BACKGROUND: It is unknown whether diltiazem, a moderate cytochrome P450 enzyme (CYP3A4) and P-glycoprotein (P-gp) inhibitor, increases the incidence of bleeding events in combination with rivaroxaban, a CYP3A4 and P-gp substrate. Diltiazem cytochrome P450 family 3 subfamily A member 4 Homo sapiens