Title : Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis.

Pub. Date : 2018 Aug 9

PMID : 30089726






1 Functional Relationships(s)
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1 Loss of CFTR-mediated HCO3- secretion reduces the pH of airway surface liquid (ASL) in vitro and in neonatal humans and pigs in vivo. Bicarbonates CF transmembrane conductance regulator Homo sapiens