Pub. Date : 2019 Aug
PMID : 30088792
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structural analysis revealed that neostigmine reaches the AChE binding site reported elsewhere, whereas fucosterol can act as a no-competitive and competitive acetylcholinesterase inhibitor, in agree with kinetic enzymatic experiments. | Neostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Binding free energy calculations revealed that fucosterol reaches the acetylcholinesterase binding site with higher affinity than neostigmine, which is according to experimental results. | Neostigmine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |