Title : Dual effect of local anesthetics on the function of excitable rod outer segment disk membrane.

Pub. Date : 1986 Apr

PMID : 3008596






1 Functional Relationships(s)
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1 The light-induced proton uptake by rhodopsin in the rod outer segment disk membrane was enhanced at lower pH (4) but depressed at higher pHs (6 to 8) by the tertiary amine local anesthetics lidocaine, bupivacaine, tetracaine, and dibucaine. Tetracaine rhodopsin Homo sapiens