Title : A Genome-Wide Screen of Deletion Mutants in the Filamentous Saccharomyces cerevisiae Background Identifies Ergosterol as a Direct Trigger of Macrophage Pyroptosis.

Pub. Date : 2018 Jul 31

PMID : 30065091






1 Functional Relationships(s)
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1 Since the mammalian sterol cholesterol triggers NLRP3-mediated pyroptosis, we hypothesized that ergosterol may also do so. Cholesterol NLR family pyrin domain containing 3 Homo sapiens