Title : Morroniside prevents H2O2 or Aβ1-42-induced apoptosis via attenuating JNK and p38 MAPK phosphorylation.

Pub. Date : 2018 Sep 5

PMID : 30059683






1 Functional Relationships(s)
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1 Exposure of PC12 cells to 150 muM H2O2 or 20 muM Abeta1-42 down-regulated anti-apoptotic protein expression (Bcl-2), up-regulated pro-apoptotic protein expression (Bax, cytochrome C, and cleaved caspase-3), increased JNK and p38 MAPK phosphorylation and finally caused significant cell death. Hydrogen Peroxide BCL2, apoptosis regulator Rattus norvegicus