Title : Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production.

Pub. Date : 2018 Jul 27

PMID : 30054566






3 Functional Relationships(s)
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1 Primary human nasal epithelial cells: a source of poly (I:C) LMW-induced IL-6 production. Poly I-C interleukin 6 Homo sapiens
2 Stimulation with Poly (I:C) LMW induced a 15 to 17 fold increase in IL-6 production by HNEC-ALI control cells (p < 0.05) and HNEC-ALI-CRS cells (p = 0.004) whilst a 2.5 fold increase was observed in CRS HNEC submerged cultures. Poly I-C interleukin 6 Homo sapiens
3 Priming of cells with Poly (I:C) LMW reduced subsequent IL-6 secretion upon stimulation with TLR 2-4 agonists. Poly I-C interleukin 6 Homo sapiens