Title : 20-HETE in the regulation of vascular and cardiac function.

Pub. Date : 2018 Dec

PMID : 30048707






1 Functional Relationships(s)
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1 20-HETE, the omega-hydroxylation product of arachidonic acid catalyzed by enzymes of the cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent effects on the vasculature including stimulation of smooth muscle cell contractility, migration and proliferation as well as activation of endothelial cell dysfunction and inflammation. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily F member 3 Homo sapiens