Pub. Date : 2018 Jul 25
PMID : 30041690
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Genetic polymorphisms of organic cation transporters 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes mellitus: a systematic review protocol. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 2 | Genetic polymorphisms of organic cation transporters 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes mellitus: a systematic review protocol. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 3 | This systematic review aims to highlight and summarize the overall effects of OCT1 polymorphisms on therapeutic responses to metformin and to evaluate their potential role in terms of interethnic differences with metformin responses. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 4 | METHODS/DESIGN: We will systematically review observational studies reporting on the genetic association between OCT1 polymorphisms and metformin responses in T2DM patients. | Metformin | solute carrier family 22 member 1 | Homo sapiens |
| 5 | DISCUSSION: This review will summarize the genetic effects of OCT1 polymorphisms associated with variabilities in glycemic responses to metformin. | Metformin | solute carrier family 22 member 1 | Homo sapiens |