Title : STAT3, a Hub Protein of Cellular Signaling Pathways, Is Triggered by β-Hexaclorocyclohexane.

Pub. Date : 2018 Jul 20

PMID : 30036966






3 Functional Relationships(s)
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1 Taking into account the pleiotropic role of the protein signal transducer and activator of transcription 3 (STAT3), its function as a hub protein in cellular signaling pathways triggered by beta-HCH was investigated in different cell lines corresponding to tissues that are especially vulnerable to damage by environmental pollutants. alpha-hexachlorocyclohexane signal transducer and activator of transcription 3 Homo sapiens
2 Taking into account the pleiotropic role of the protein signal transducer and activator of transcription 3 (STAT3), its function as a hub protein in cellular signaling pathways triggered by beta-HCH was investigated in different cell lines corresponding to tissues that are especially vulnerable to damage by environmental pollutants. alpha-hexachlorocyclohexane signal transducer and activator of transcription 3 Homo sapiens
3 RESULTS AND CONCLUSIONS: The preliminary results allow us to hypothesize the involvement of STAT3, through both its canonical and non-canonical pathways, in response to beta-HCH. alpha-hexachlorocyclohexane signal transducer and activator of transcription 3 Homo sapiens