Title : Target-programmed and autonomous proximity binding aptasensor for amplified electronic detection of thrombin.

Pub. Date : 2018 Oct 15

PMID : 30014949






2 Functional Relationships(s)
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1 The binding of thrombin to the aptamer sequences in the partial dsDNA duplex probes induces the release of the ssDNA trigger strands, which catalyze subsequent assembly formation of many methylene blue (MB)-tagged proximate DNA motifs with the presence of the DNA fuel strands through cascaded toehold-mediated strand displacement reactions. Methylene Blue coagulation factor II, thrombin Homo sapiens
2 The binding of thrombin to the aptamer sequences in the partial dsDNA duplex probes induces the release of the ssDNA trigger strands, which catalyze subsequent assembly formation of many methylene blue (MB)-tagged proximate DNA motifs with the presence of the DNA fuel strands through cascaded toehold-mediated strand displacement reactions. Methylene Blue coagulation factor II, thrombin Homo sapiens