Title : E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53.

Pub. Date : 2018

PMID : 30003124






1 Functional Relationships(s)
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1 Background & Aims: Oncogenic mutations in KRAS, coupled with inactivation of p53, CDKN2A/p16INK4A, and SMAD4, drive progression of pancreatic ductal adenocarcinoma (PDA). Adenosine Monophosphate tumor protein p53 Homo sapiens