Pub. Date : 2018
PMID : 29996716
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose. | Trehalose | transcription factor EB | Mus musculus |
| 2 | Here, we demonstrate that trehalose induces hepatocyte TFEB (transcription factor EB)-dependent thermogenesis in vivo, concomitant with upregulation of hepatic and white adipose expression of UCP1 (uncoupling protein 1 [mitochondrial, protein carrier]). | Trehalose | transcription factor EB | Mus musculus |
| 3 | Here, we demonstrate that trehalose induces hepatocyte TFEB (transcription factor EB)-dependent thermogenesis in vivo, concomitant with upregulation of hepatic and white adipose expression of UCP1 (uncoupling protein 1 [mitochondrial, protein carrier]). | Trehalose | transcription factor EB | Mus musculus |
| 4 | Strikingly, hepatocyte-selective TFEB knockdown abrogated trehalose induction of thermogenesis and white adipose tissue UCP1 upregulation in vivo. | Trehalose | transcription factor EB | Mus musculus |