Title : Upregulated IQUB promotes cell proliferation and migration via activating Akt/GSK3β/β-catenin signaling pathway in breast cancer.

Pub. Date : 2018 Aug

PMID : 29968965






1 Functional Relationships(s)
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1 Furthermore, IQUB overexpression or knockdown combined with treatment of Licl or MG-132 showed that IQUB activated Akt to promote GSK3beta phosphorylation, which in turn activated Wnt/beta-catenin signaling pathway in breast cancer cells. Lithium Chloride glycogen synthase kinase 3 beta Homo sapiens