Pub. Date : 2018 Sep
PMID : 29960031
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A new xanthatin analogue 1beta-hydroxyl-5alpha-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | A new xanthatin analogue 1beta-hydroxyl-5alpha-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | ROS scavenger N-acetyl cysteine abrogated the effects of XTT on ERK/p38 MAPK activation and JAK2/STAT3 inhibition, and rescued HCC cells from XTT-induced apoptosis. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 4 | ROS scavenger N-acetyl cysteine abrogated the effects of XTT on ERK/p38 MAPK activation and JAK2/STAT3 inhibition, and rescued HCC cells from XTT-induced apoptosis. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 5 | In summary, XTT inhibited cell growth and induced apoptosis in HCC cells through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition by GSH depletion. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 6 | In summary, XTT inhibited cell growth and induced apoptosis in HCC cells through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition by GSH depletion. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |