Pub. Date : 2018 Nov
PMID : 29934672
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structure-activity relationship investigation of coumarin-chalcone hybrids with diverse side-chains as acetylcholinesterase and butyrylcholinesterase inhibitors. | coumarin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Here, we report the synthesis and testing of 36 new coumarin-chalcone hybrids (5d-7j, 9d-11f, 12k-13m) against AChE and BChE. | coumarin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | Overall, the results show that coumarin-chalcone hybrids with choline-like side-chains have promising activity and selectivity against AChE and be promising therapeutic leads for Alzheimer"s disease. | coumarin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |