Title : New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors.

Pub. Date : 2018 Aug 14

PMID : 29934490






1 Functional Relationships(s)
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1 We exploit ligand binding and inhibitor screens to uncover a susceptibility of TPST1 and TPST2 to different classes of small molecules, including the anti-angiogenic compound suramin and the kinase inhibitor rottlerin. rottlerin tyrosylprotein sulfotransferase 1 Homo sapiens