Title : C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer.

Pub. Date : 2018 Oct

PMID : 29930379






1 Functional Relationships(s)
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1 Blocking O-glycan elongation on EGFR by C1GALT1 knockdown decreases EGF-EGFR binding affinity and inhibits EGFR signaling, thereby suppressing malignant phenotypes. o-glycan core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Homo sapiens