Title : EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains.

Pub. Date : 2018 Jul 17

PMID : 29928795






1 Functional Relationships(s)
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1 Results of GST pull-down and fluorescence polarization assays show that both a proline-rich SH3 binding motif (PSRPLPDAP, residues 466-474) and an adjacent phosphotyrosine-containing SH2 binding motif (pYEEI, residues 508-511) in Tks4 are responsible for Src binding. Proline SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens