Title : An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors.

Pub. Date : 2018 Jun 14

PMID : 29904056






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Pyridone-containing inhibitors such as GSK126 compete with S-adenosylmethionine (SAM) for Ezh2 binding and effectively inhibit PRC2 activity. S-Adenosylmethionine enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens
2 Pyridone-containing inhibitors such as GSK126 compete with S-adenosylmethionine (SAM) for Ezh2 binding and effectively inhibit PRC2 activity. S-Adenosylmethionine enhancer of zeste 2 polycomb repressive complex 2 subunit Homo sapiens