Title : Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity.

Pub. Date : 2018 May 25

PMID : 29899847






1 Functional Relationships(s)
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Protein Name
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1 HSP90 inhibitors suppressed ubiquitination processes which were involved in p53 degradation, but a proteasome inhibitor, MG-132, prevented the HSP90 inhibitors-induced p53 down-regulation. benzyloxycarbonylleucyl-leucyl-leucine aldehyde tumor protein p53 Homo sapiens