Title : The effect of chloride on the redox and EPR properties of myeloperoxidase.

Pub. Date : 1985 Jul 15

PMID : 2989285






4 Functional Relationships(s)
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1 The effect of chloride on the redox and EPR properties of myeloperoxidase. Chlorides myeloperoxidase Homo sapiens
2 Myeloperoxidase was purified from human polymorphonuclear leukocytes and the effect of chloride upon the EPR and potentiometric properties was studied. Chlorides myeloperoxidase Homo sapiens
3 Myeloperoxidase exhibited a rhombic high spin EPR signal which exhibited reduced rhombicity upon the binding of chloride. Chlorides myeloperoxidase Homo sapiens
4 Our results strongly suggest that chloride binds to the sixth coordination position of the chlorin iron in myeloperoxidase by replacing the water which is the sixth ligand in the resting state. Chlorides myeloperoxidase Homo sapiens