Title : Chlorination of NADH: similarities of the HOCl-supported and chloroperoxidase-catalyzed reactions.

Pub. Date : 1985 May 15

PMID : 2988446






2 Functional Relationships(s)
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1 These data indicate that, with respect to halogenation activities, chloroperoxidase functions similarly to myeloperoxidase, i.e., produces HOCl as the first product of Cl- oxidation by H2O2. Hypochlorous Acid myeloperoxidase Homo sapiens
2 Moreover, rapid chlorination of NAD(P)H followed by oxidation may be an important and highly lethal microbicidal effect of HOCl produced by myeloperoxidase in activated neutrophils. Hypochlorous Acid myeloperoxidase Homo sapiens