Pub. Date : 2018 Oct
PMID : 29884090
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Repurposing a Histamine Detection Platform for High-Throughput Screening of Histidine Decarboxylase. | Histamine | histidine decarboxylase | Homo sapiens |
| 2 | Histidine decarboxylase (HDC) is the primary enzyme that catalyzes the conversion of histidine to histamine. | Histamine | histidine decarboxylase | Homo sapiens |
| 3 | Histidine decarboxylase (HDC) is the primary enzyme that catalyzes the conversion of histidine to histamine. | Histamine | histidine decarboxylase | Homo sapiens |
| 4 | HDC contributes to many physiological responses as histamine plays important roles in allergic reaction, neurological response, gastric acid secretion, and cell proliferation and differentiation. | Histamine | histidine decarboxylase | Homo sapiens |
| 5 | Small-molecule modulation of HDC represents a potential therapeutic strategy for a range of histamine-associated diseases, including inflammatory disease, neurological disorders, gastric ulcers, and select cancers. | Histamine | histidine decarboxylase | Homo sapiens |
| 6 | The assay is based on competition between HDC-generated histamine and fluorophore-labeled histamine for binding to a Europium cryptate (EuK)-labeled anti-histamine antibody. | Histamine | histidine decarboxylase | Homo sapiens |