Title : Differential Effects of Statins on Inflammatory Interleukin-8 and Antimicrobial Peptide Human Β-Defensin 2 Responses in Salmonella-Infected Intestinal Epithelial Cells.

Pub. Date : 2018 Jun 2

PMID : 29865262






1 Functional Relationships(s)
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1 Akt or VDR knockdown by siRNA counteracted the suppressive effect of simvastatin on IL-8 expression, whereas VDR knockdown diminished the enhanced hBD-2 expression in Salmonella-infected SW480 cells. Simvastatin AKT serine/threonine kinase 1 Homo sapiens