Title : Novel action of vinpocetine in the prevention of paraquat-induced parkinsonism in mice: involvement of oxidative stress and neuroinflammation.

Pub. Date : 2018 Oct

PMID : 29855979






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1 In addition, paraquat injection caused marked increase in nitroso-oxidative stress markers with concomitant deficits in antioxidant enzymes activities (GSH and SOD) as well as induction of tumour necrotic factor-alpha (TNF-alpha) in the mid-brain which were attenuated by the pretreatment of mice with vinpocetine. Paraquat tumor necrosis factor Mus musculus