Title : A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of in vitro and in silico analyses.

Pub. Date : 2018 Mar

PMID : 29854877






2 Functional Relationships(s)
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1 For initial screening, we screened 5,000 genes through selection of shRNAs in p53 wild-type tumor cells that altered sensitivity to the p53 activator actinomycin D (ActD) to identify p53 regulatory genes; shRNAs targeting 322 genes were obtained. Dactinomycin tumor protein p53 Homo sapiens
2 For initial screening, we screened 5,000 genes through selection of shRNAs in p53 wild-type tumor cells that altered sensitivity to the p53 activator actinomycin D (ActD) to identify p53 regulatory genes; shRNAs targeting 322 genes were obtained. Dactinomycin tumor protein p53 Homo sapiens