Title : Effects of epidermal growth factor on acid secretion from guinea pig gastric mucosa: in vitro analysis.

Pub. Date : 1985 May

PMID : 2984079






3 Functional Relationships(s)
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1 Epidermal growth factor reduced the rate of histamine-induced acid secretion to near basal levels when applied to the serosal gastric surface at nanomolar concentrations. Histamine pro-epidermal growth factor Cavia porcellus
2 Cyclic adenosine monophosphate-induced secretion was also reduced by EGF, although the effect occurred more slowly than in histamine-treated tissues. Histamine pro-epidermal growth factor Cavia porcellus
3 Epidermal growth factor increased transmucosal resistance in histamine-treated, but not cyclic adenosine monophosphate-treated mucosa; potential difference was unaffected. Histamine pro-epidermal growth factor Cavia porcellus