Title : Nicotinamide N-methyltransferase enhances the progression of prostate cancer by stabilizing sirtuin 1.

Pub. Date : 2018 Jun

PMID : 29805651






2 Functional Relationships(s)
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1 In addition, nicotinamide treatment significantly suppressed the expression of SIRT1 even in PC-3 cells transfected with adeno-associated virus-NNMT. Niacinamide nicotinamide N-methyltransferase Homo sapiens
2 Furthermore, the PC-3 cell invasion capacity was notably decreased by the nicotinamide treatment; however, such effects were largely abolished by the overexpression of NNMT in PC-3 cells. Niacinamide nicotinamide N-methyltransferase Homo sapiens