Title : SIRT1 reverses senescence via enhancing autophagy and attenuates oxidative stress-induced apoptosis through promoting p53 degradation.

Pub. Date : 2018 Oct 1

PMID : 29803744






2 Functional Relationships(s)
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1 Co-immunoprecipitation assay showed that SIRT1 could bind to p53, reduce its acetylation level, and treatment with nutlin-3A reversed the effect of SIRT1 on the level of p53 in ADSCs. nutlin 3 tumor protein p53 Homo sapiens
2 Co-immunoprecipitation assay showed that SIRT1 could bind to p53, reduce its acetylation level, and treatment with nutlin-3A reversed the effect of SIRT1 on the level of p53 in ADSCs. nutlin 3 tumor protein p53 Homo sapiens