Title : Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine.

Pub. Date : 2018 May 24

PMID : 29795412






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Leucine starvation suppressed polysome formation and was the only tested condition that caused a significant decrease in 4EBP1 phosphorylation or increase in 4EBP1 binding to eIF4E, but effects of leucine starvation were not replicated by overexpressing nonphosphorylatable 4EBP1. Leucine eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens
2 Leucine starvation suppressed polysome formation and was the only tested condition that caused a significant decrease in 4EBP1 phosphorylation or increase in 4EBP1 binding to eIF4E, but effects of leucine starvation were not replicated by overexpressing nonphosphorylatable 4EBP1. Leucine eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens
3 Leucine starvation suppressed polysome formation and was the only tested condition that caused a significant decrease in 4EBP1 phosphorylation or increase in 4EBP1 binding to eIF4E, but effects of leucine starvation were not replicated by overexpressing nonphosphorylatable 4EBP1. Leucine eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens