Pub. Date : 2018 May 24
PMID : 29795382
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Retinoic acid (RA) and arsenic target the t(15;17)(q24;q21) PML/RARA driver of acute promyelocytic leukemia (APL), their combination now curing over 95% patients. | Tretinoin | PML nuclear body scaffold | Homo sapiens |
| 2 | Retinoic acid (RA) and arsenic target the t(15;17)(q24;q21) PML/RARA driver of acute promyelocytic leukemia (APL), their combination now curing over 95% patients. | Tretinoin | PML nuclear body scaffold | Homo sapiens |
| 3 | Accordingly, clonogenic activity of PML/RARA-immortalized progenitors ex vivo is only transiently affected by RA, but selectively abrogated by arsenic. | Tretinoin | PML nuclear body scaffold | Homo sapiens |