Pub. Date : 2018 May 22
PMID : 29789538
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Salvianolic acid B inhibits glycolysis in oral squamous cell carcinoma via targeting PI3K/AKT/HIF-1alpha signaling pathway. | salvianolic acid B | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Rescue assays suggested that compared with Sal-B treatment group, Akt or hif-1a overexpression attenuated the inhibitory effect of Sal-B on glucose uptake and intracellular lactate level. | salvianolic acid B | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Taken together, our results suggested that Sal-B modulated aberrant glucose metabolism via the PI3K/AKT/HIF-1alpha signaling pathways, which might contribute to the anti-carcinogenic activity of Sal-B. | salvianolic acid B | AKT serine/threonine kinase 1 | Homo sapiens |