Pub. Date : 2018 Sep
PMID : 29777777
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As verified using Immunoblotting assays, miR-128 significantly regulated the protein levels of VEGFC/VEGFR3, whereas miR-3916 only slightly modulated VEGFC and VEGFR3 proteins. | mir-128 | vascular endothelial growth factor C | Homo sapiens |
| 2 | Contrary to VEGFC, miR-128 overexpression remarkably suppressed LEC proliferation, Ca2+ release and ERK1/2-Akt signaling; moreover, the effect of VEGFC could be partially attenuated by miR-128. | mir-128 | vascular endothelial growth factor C | Homo sapiens |
| 3 | Contrary to VEGFC, miR-128 overexpression remarkably suppressed LEC proliferation, Ca2+ release and ERK1/2-Akt signaling; moreover, the effect of VEGFC could be partially attenuated by miR-128. | mir-128 | vascular endothelial growth factor C | Homo sapiens |
| 4 | In summary, miR-128 interacts with the 3"-UTR of VEGFC and VEGFR3 to inhibit their expression, thus suppressing LEC proliferation through Ca2+ and ERK1/2-Akt signaling. | mir-128 | vascular endothelial growth factor C | Homo sapiens |