Title : Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase.

Pub. Date : 2018 Sep

PMID : 29775949






1 Functional Relationships(s)
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1 The Lineweaver-Burk plot and docking study showed that compound 5 h targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Aminosalicylic Acid acetylcholinesterase (Cartwright blood group) Homo sapiens