Title : Inhibition of T-cell antigen receptor-mediated transmembrane signaling by protein kinase C activation.

Pub. Date : 1988 Dec

PMID : 2977423






1 Functional Relationships(s)
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1 Although 12-O-tetradecanoylphorbol-13-acetate (TPA) was capable of replacing IL-1 as an activating stimulus under certain conditions, biologic studies indicated that TPA failed to synergize with Ti-CD3-dependent stimuli under conditions in which IL-1 was clearly active. Tetradecanoylphorbol Acetate interleukin 1 complex Mus musculus