Title : Estrogenic properties of coumarins and meroterpene from the fruits of Cullen corylifolium: Experimental and computational studies.

Pub. Date : 2018 Aug

PMID : 29772410






2 Functional Relationships(s)
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1 Coumarins and meroterpene from the fruits of Cullen corylifolium were evaluated for their ability to bind and activate human estrogen receptor alpha (hERalpha) by a combination of in vitro studies and molecular dynamics simulations. Coumarins estrogen receptor 1 Homo sapiens
2 In an estrogen response element-luciferase (ERE-Luc) reporter gene assay, coumarins and meroterpene acted as agonists of human estrogen receptor alpha. Coumarins estrogen receptor 1 Homo sapiens