Title : Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)2D3.

Pub. Date : 2018

PMID : 29771914






1 Functional Relationships(s)
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1 Vitamin D is first modified in the liver by the 25-hydroxylases CYP2R1 and CYP27A1 and further activated in the kidney by the 1alpha-hydroxylase CYP27B1, while the renal 24-hydroxylase CYP24A1 catalyzes the first step of its inactivation. Vitamin D cytochrome P450, family 24, subfamily a, polypeptide 1 Mus musculus