Title : Type 2 Diabetes Promotes Cell Centrosome Amplification via AKT-ROS-Dependent Signalling of ROCK1 and 14-3-3σ.

Pub. Date : 2018

PMID : 29768267






1 Functional Relationships(s)
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1 Results from further analyses showed that AKT-ROS-dependent upregulations of expression, binding and centrosome translocation of ROCK1 and 14-3-3sigma was the molecular pathway underlying the centrosome amplification in vitro triggered by high glucose, insulin and palmitic acid. Palmitic Acid AKT serine/threonine kinase 1 Homo sapiens