Title : Inhibitory effects of histamine on interleukin 2 and gamma interferon production of different human T helper cell subsets.

Pub. Date : 1988 Dec

PMID : 2976521






3 Functional Relationships(s)
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1 Histamine was shown to suppress to a similar extent the production of interleukin 2 (IL-2) and gamma interferon (IFN-gamma) by Leu 3+, Leu 3+8+, and Leu 3+8- cell subsets. Histamine interferon gamma Homo sapiens
2 The IFN-gamma production by the Leu 3+ and Leu 3+18- cells and the marginal production by Leu 3+18+ cells were significantly suppressed by histamine. Histamine interferon gamma Homo sapiens
3 It was shown that the inhibitory effect of histamine on the early production of IL-2 and the major production of IFN-gamma by T helper cells is mediated via action on both the Leu 3+18-8- and the Leu 3+18-8+ cells. Histamine interferon gamma Homo sapiens