Title : Glucocorticoid receptor gene variants and lower expression of NR3C1 are associated with cocaine use.

Pub. Date : 2019 Jul

PMID : 29761890






2 Functional Relationships(s)
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1 As the glucocorticoid receptor gene (NR3C1) mediates genomic effects of the stress hormone cortisol, we investigated NR3C1 expression and the association of NR3C1 genotypes with cocaine use, addiction and comorbid psychiatric symptoms in 126 chronic cocaine users and 98 stimulant-naive healthy controls. Hydrocortisone nuclear receptor subfamily 3 group C member 1 Homo sapiens
2 As the glucocorticoid receptor gene (NR3C1) mediates genomic effects of the stress hormone cortisol, we investigated NR3C1 expression and the association of NR3C1 genotypes with cocaine use, addiction and comorbid psychiatric symptoms in 126 chronic cocaine users and 98 stimulant-naive healthy controls. Hydrocortisone nuclear receptor subfamily 3 group C member 1 Homo sapiens