Title : Discovery of Natural Products as Novel and Potent FXR Antagonists by Virtual Screening.

Pub. Date : 2018

PMID : 29761098






1 Functional Relationships(s)
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1 The IC50 values of compounds 2a, a diterpene bearing polycyclic skeleton, and 3a, named daphneone with chain scaffold, are as low as 1.29 and 1.79 muM, respectively. Diterpenes latexin Homo sapiens