Title : DNA triplex structure, thermodynamics, and destabilisation: insight from molecular simulations.

Pub. Date : 2018 May 23

PMID : 29744501






2 Functional Relationships(s)
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1 A structural analysis of the DNA triplexes that can form with the FRDA-related duplex sequence indicates that the triplex with a parallel homopyrimidine TFO is likely to be more stable than the antiparallel homopurine-TFO triplex, which may have implications for disease onset and treatment. tfo frataxin Homo sapiens
2 A structural analysis of the DNA triplexes that can form with the FRDA-related duplex sequence indicates that the triplex with a parallel homopyrimidine TFO is likely to be more stable than the antiparallel homopurine-TFO triplex, which may have implications for disease onset and treatment. tfo frataxin Homo sapiens