Title : Covalent inhibitors of nicotinamide N-methyltransferase (NNMT) provide evidence for target engagement challenges in situ.

Pub. Date : 2018 Sep 1

PMID : 29731364






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor and, through doing so, can modulate cellular methylation potential to impact diverse epigenetic processes. Niacinamide nicotinamide N-methyltransferase Homo sapiens
2 Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor and, through doing so, can modulate cellular methylation potential to impact diverse epigenetic processes. Niacinamide nicotinamide N-methyltransferase Homo sapiens