Title : Retinoic acid regulates IgG Fc receptor expression in human myelomonocytic leukemia cells and normal peripheral monocytes.

Pub. Date : 1988 Sep

PMID : 2972558






3 Functional Relationships(s)
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Protein Name
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1 RA suppressed IgG-coated erythrocyte (EA) rosette formation of myelomonocytic cells blocked at relatively late stages of differentiation such as ML-1, U-937, THP-1-T, normal monocytes, and fresh cells of patients with acute myelomonocytic leukemia. Tretinoin GLI family zinc finger 2 Homo sapiens
2 A kinetic study using HL-60 and THP-1-T demonstrated that an increase required at least a 48-h exposure and that the maximum decrease required approximately 6 h. The RA effect on both cell lines was dose-dependent. Tretinoin GLI family zinc finger 2 Homo sapiens
3 The number of Fc gamma R of HL-60 and THP-1-T treated with RA became very close, although untreated THP-1 had almost 10 times as many as HL-60. Tretinoin GLI family zinc finger 2 Homo sapiens