Pub. Date : 2018
PMID : 29721956
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We previously reported that heat shock protein 70 (HSP70), which has a protective effect on neuronal cells, was cleaved by a calcium-dependent protease, calpain, in N-methyl-N-nitrosourea (MNU)-treated mice retina. | Methylnitrosourea | heat shock protein 1B | Mus musculus |
2 | We previously reported that heat shock protein 70 (HSP70), which has a protective effect on neuronal cells, was cleaved by a calcium-dependent protease, calpain, in N-methyl-N-nitrosourea (MNU)-treated mice retina. | Methylnitrosourea | heat shock protein 1B | Mus musculus |
3 | We previously reported that heat shock protein 70 (HSP70), which has a protective effect on neuronal cells, was cleaved by a calcium-dependent protease, calpain, in N-methyl-N-nitrosourea (MNU)-treated mice retina. | Methylnitrosourea | heat shock protein 1B | Mus musculus |
4 | We previously reported that heat shock protein 70 (HSP70), which has a protective effect on neuronal cells, was cleaved by a calcium-dependent protease, calpain, in N-methyl-N-nitrosourea (MNU)-treated mice retina. | Methylnitrosourea | heat shock protein 1B | Mus musculus |
5 | Therefore, protein carbonylation and subsequent calpain-dependent cleavage of HSP70 are key events in MNU-mediated photoreceptor cell death. | Methylnitrosourea | heat shock protein 1B | Mus musculus |