Title : The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.

Pub. Date : 2018 Apr 27

PMID : 29703933






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Cysteine superoxide dismutase 1 Homo sapiens
2 Here we report that the cysteine-reactive molecule ebselen efficiently confers the SOD1 intra-subunit disulphide and directs correct SOD1 folding, depopulating the globally unfolded precursor associated with aggregation and toxicity. Cysteine superoxide dismutase 1 Homo sapiens
3 Here we report that the cysteine-reactive molecule ebselen efficiently confers the SOD1 intra-subunit disulphide and directs correct SOD1 folding, depopulating the globally unfolded precursor associated with aggregation and toxicity. Cysteine superoxide dismutase 1 Homo sapiens